The eight greatest antivirus programmes for Windows 10 Bitdefender Antivirus Plus. The best antivirus software for Windows 10 is packed to the gills with features. Norton AntiVirus Plus. Antivirus Plus Protection from Trend Micro. Anti-Virus Protection for Windows from Kaspersky Lab. Avira Antivirus Pro. Avast Premium Security is the software. McAfee Total Protection is also available. BullGuard Antivirus.